Conventional gold nanoparticles-based lateral flow immunoassays (AuNPs-LFIA) lack sensitivity. In this work, we developed a graphite-like carbon nitride-laden AuNPs (g-C3N4@Au) assisted LFIA to improve sensitivity for 17β-estradiol (E2) in foods. g-C3N4 nanosheets were applied as carriers, because of their excellent chemical stability, large surface areas and low-cost, loading large numbers of AuNPs to amplify signals and improve the overall response of g-C3N4@Au-based LFIA (g-C3N4@Au-LFIA). The lowest visual limit of detection (vLOD) of E2 is 0.5 ng mL-1 for g-C3N4@Au-LFIA, which exhibit a significantly three-fold improved analytical performance compared with that of AuNPs-LFIA. Additionally, this method was successfully used to the detection of E2 in four spiked food samples, offering a great potential of the g-C3N4@Au based LFIA for its application in food products.Pesticide adjuvants (PAs) are important components of pesticide products. However, limited information is available regarding their occurrences in foodstuffs. Herein, eight common-used PAs were investigated in vegetables in North China in 2014-2016. GNE-317 purchase The residue levels of total PAs in vegetables from markets and farms were 500 and 661 μg/kg, respectively. The highest residues of total PAs were found in cauliflowers (average 1.53 × 103 μg/kg, market vegetables) and spinaches (average 3.72 × 103 μg/kg, farm vegetables), respectively. In addition, Tristyrylphenol ethoxylates (TPE) dominated the total 8 PAs concentrations in most vegetable species. Moreover, the risk assessment showed that the human health risks associated with TPE and nonylphenol (NP) exposure via vegetables for adults were acceptable, and the estimated daily intakes (EDIs) of other six PAs were in the range of less then 0.010-0.89 μg/kg bw/day, which were less likely to pose a threat to human health.The Hellenic Food Thesaurus (HelTH) is the first systematic attempt to create a Greek Branded Food Composition Database. Data on the nutritional composition of foods for up to 45 nutrients, on-pack claims (health, nutrition, social, environmental), quality indicators, and prices were recorded for more than 4,000 foods as they appear on the photographs of their packages available on retailers' websites. A group of trained researchers carried out data collection and classification using LanguaL. HelTH highlights the variability in nutritional compositions of packaged foods in Greece and the need for better labelling of key nutrients such as trans fatty acids. According to a preliminary analysis of on-pack communications (n = 2008 products), health claims are used rarely (4.1% of products analyzed) with greater prevalence of nutrition (~32%) and natural claims (~24%). HelTH is a key infrastructure for the implementation of food and nutrition policies, new product development, and nutrition and consumer research.Caoyuanwang Baijiu (CYW), a mild-flavor style Baijiu (MSB), is popular in northern China. However, there is a lack of studies reporting its aroma-active components. The aroma compounds of five CYW samples were analyzed using gas chromatography-olfactory-mass spectrometry coupled with aroma extraction dilution analysis. Fifty-five aroma-active compounds were identified in CYW, of which 27 had odor activity values ≥ 1. Reconstituted models successfully simulated the aroma profiles of CYW. The omission tests elucidated that β-damascenone, dimethyl trisulfide, ethyl pentanoate, butanoic acid, ethyl acetate, 3-methylbutanal, ethyl lactate, hexanoic acid, γ-nonalactone, 3-hydroxy-2-butanone, ethyl butanoate, 1-propanol, 4-(ethoxymethyl)-2-methoxy-phenol, and vanillin were key odorants in CYW. The addition test confirmed the significant influence of dimethyl trisulfide on Chen-aroma note. Nine key odorants were identified as the differential quality-markers, and 85.71% key odorants were predicted using the partial least square regression (PLSR) analysis, indicating the applicability of PLSR in selecting the target compounds for omission tests.Trichloroacetic acid (TCAA) is a common disinfection byproduct (DBP) produced during chlorine disinfection. With the outbreak of the Coronavirus Disease 2019 (COVID-19) pandemic, the use of chlorine disinfection has increased, raising the already substantial risks of DBP exposure. While a number of methods are able to remove TCAA, their application for continuous treatment is limited due to their complexity and expensive or hazardous inputs. We investigated a novel system that employs palladium (Pd0) nanoparticles (PdNPs) for catalytic reductive dechlorination of TCAA. H2 was delivered directly to PdNPs in situ coated on the surface of bubble-free hollow-fiber gas-transfer membranes. The H2-based membrane Pd film reactor (H2-MPfR) achieved a high catalyst-specific TCAA reduction rate, 32 L/g-Pd/min, a value similar to the rate of using homogeneously suspended PdNP, but orders of magnitude higher than with other immobilized PdNP systems. In batch tests, over 99% removal of 1 mM TCAA was achieved in 180 min with strong product selectivity (≥ 93%) to acetic acid. During 50 days of continuous operation, over 99% of 1 mg/L influent TCAA was removed, again with acetic acid as the major product (≥ 94%). We identified the reaction pathways and their kinetics for TCAA reductive dechlorination with PdNPs using direct delivery of H2. Sustained continuous TCAA removal, high selectivity to acetic acid, and minimal loss of PdNPs support that the H2-MPfR is a promising catalytic reactor to remove chlorinated DBPs in practice.
Nasopharyngeal carcinoma (NPC) is common in Southeast Asia. Due to the influx of immigrants from this region, the incidence in British Columbia is increasing. Current literature from non-endemic populations encompasses heterogeneous cohorts. This study examines NPC in a North American population, with a high incidence, to understand the population's characteristics, treatment outcomes and recurrence patterns.

A retrospective analysis of patients treated for primary and recurrent NPC over 15-years. Regression analyses were used to identify predictors of disease recurrence and death. A subgroup analysis of the locoregional recurrence cohort was conducted. Five-year survival outcomes were determined.

601 patients were included. Asian ethnicity comprised 77% and the majority had non-keratinizing carcinoma (81%). In total, 19.3% of patients experienced recurrence 58% local, 22% regional and 20% distant. Five-year overall survival was 70%. Smoking, advancing T-stage, poorer performance status and advanced overall stage were all associated with worse overall survival (p<0.GNE-317 purchase